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Blue Sky Mental Health Clinic

Spravato® esketamine treatment

Spravato Treatment in Maryland & Washington, DC

When depression has not improved enough with previous treatment, Spravato may be an option worth discussing with a psychiatric provider.

Blue Sky provides supervised Spravato treatment at its locations in Silver Spring, MD; Laurel, MD; and Washington, DC. All three offices are certified in the SPRAVATO REMS program.

Request a Spravato EvaluationCall Blue Sky

A psychiatric evaluation is required to determine whether Spravato is appropriate for you.

A closer look

Medically reviewed by Jason Eliassaint, PMHNP-BC

Psychiatric-Mental Health Nurse Practitioner · Founder & Clinical Director

Blue Sky Mental Health Clinic

Last reviewed:

In brief

Key facts, clearly.

  • 01Spravato® (esketamine) is an FDA-approved prescription nasal spray for adults with treatment-resistant depression.
  • 02Current FDA labeling permits Spravato to be used for treatment-resistant depression either alone or with an oral antidepressant.
  • 03It is administered under supervision in a certified healthcare setting, not at home.
  • 04Patients are monitored for at least two hours after each session.
  • 05A psychiatric evaluation is required to assess whether it may be appropriate.

Sources: FDA drug record and prescribing information · SPRAVATO REMS

When depression hasn’t improved enough

There may be another treatment option.

Some people continue experiencing significant depression symptoms even after trying previous treatments. Spravato is a prescription esketamine nasal spray approved for certain adults with treatment-resistant depression.

Current FDA labeling allows use either alone or with an oral antidepressant for treatment-resistant depression. An evaluation helps a provider understand your treatment history and whether this approach might fit your care plan.

Request a Spravato Evaluation

Understanding the treatment

What is Spravato?

Spravato is the brand name for esketamine nasal spray. Esketamine is related to ketamine, but Spravato is a distinct FDA-approved medication with its own administration and safety requirements.

FDA materials identify risks including sedation, dissociation, respiratory depression, and abuse or misuse. Because of these risks, it is available through the restricted SPRAVATO REMS program and must be administered under supervision in a certified healthcare setting.

FDA prescribing information SPRAVATO REMS

Individual assessment

Could Spravato be right for you?

It may be considered for some adults whose depression has not responded adequately to previous treatment. Not everyone will be a candidate.

A provider may review:

  • Current symptoms
  • Previous depression treatments
  • Current medications
  • Psychiatric and medical history
  • Response to treatment
  • Possible safety concerns
  • Broader treatment goals

The purpose of an evaluation is to determine which approach makes sense for you, not to automatically prescribe Spravato.

Request a Spravato Evaluation

What to expect

Your Spravato treatment process

  1. 01

    Psychiatric evaluation

    A provider reviews your symptoms, prior treatment, medications, medical history, and relevant safety considerations.

  2. 02

    Treatment planning

    If Spravato is appropriate, your care team explains the treatment schedule, preparation, monitoring, and alternatives.

  3. 03

    Supervised treatment

    Spravato is administered as a nasal spray under healthcare supervision in a certified healthcare setting. It is not taken home.

  4. 04

    Post-treatment monitoring

    Patients are monitored for at least two hours after each treatment session.

  5. 05

    Ongoing clinical review

    A provider assesses response and tolerability over time and considers whether the care plan needs to change.

Evaluation coordination

Spravato Treatment Near You in Maryland & Washington, DC

Blue Sky Mental Health Clinic provides supervised SPRAVATO® (esketamine) treatment in healthcare settings certified in the SPRAVATO REMS in Silver Spring, Laurel, and Washington, DC. Choose your preferred office when requesting an evaluation; a psychiatric provider will determine whether treatment may be appropriate for you.

Spravato treatment available

Spravato Treatment in Silver Spring, MD

Blue Sky Mental Health Clinic
10301 Georgia Ave, Suite 203W
Silver Spring, MD 20902

Blue Sky Mental Health Clinic provides supervised SPRAVATO® (esketamine) treatment in Silver Spring, Maryland for eligible adults. Treatment begins with a psychiatric evaluation to determine whether SPRAVATO may be appropriate. When prescribed, SPRAVATO is administered in the clinic under direct observation, followed by the required post-treatment monitoring.

Request a Spravato EvaluationView Silver Spring Office

Spravato treatment available

Spravato Treatment in Laurel, MD

Blue Sky Mental Health Clinic
14504 Greenview Drive, Suite 202
Laurel, MD 20708

Blue Sky Mental Health Clinic provides supervised SPRAVATO® (esketamine) treatment in Laurel, Maryland for eligible adults. Treatment begins with a psychiatric evaluation to determine whether SPRAVATO may be appropriate. When prescribed, SPRAVATO is administered in the clinic under direct observation, followed by the required post-treatment monitoring.

Request a Spravato EvaluationView Laurel Office

Spravato treatment available

Spravato & Esketamine Treatment in Washington, DC

Blue Sky Mental Health Clinic
3831 Pennsylvania Ave, Southeast
Washington, DC 20020

Blue Sky Mental Health Clinic provides supervised SPRAVATO® (esketamine) treatment in Washington, DC for eligible adults. Treatment begins with a psychiatric evaluation to determine whether SPRAVATO may be appropriate. When prescribed, SPRAVATO is administered in the clinic under direct observation, followed by the required post-treatment monitoring.

Request a Spravato EvaluationView Washington, DC Office

Required safety program

SPRAVATO REMS-Certified Treatment

SPRAVATO® is available through a restricted Risk Evaluation and Mitigation Strategy (REMS) program. Blue Sky Mental Health Clinic provides SPRAVATO treatment in healthcare settings certified in the SPRAVATO REMS. Treatment is administered under the direct observation of a healthcare provider, and patients are monitored for at least two hours after administration.

SPRAVATO is not dispensed to patients for at-home use.

REMS certification is a required safety-program certification, not a quality award or ranking.

Official SPRAVATO REMS resource

Safety & supervision

Why Spravato is given in a clinic

Treatment includes supervision for a reason.

Spravato has important safety considerations. FDA labeling and REMS requirements describe risks including sedation, dissociation, respiratory depression, and abuse or misuse. This is why administration and observation happen in a certified healthcare setting.

Is Spravato the same as ketamine?

No. Spravato contains esketamine, which is related to ketamine, but it is a distinct FDA-approved nasal spray with specific approved uses and REMS requirements. Ketamine itself is not FDA-approved to treat psychiatric disorders.

Why Blue Sky

More than a Spravato clinic.

Treatment-resistant depression is rarely just about choosing one medication. Blue Sky also provides psychiatric care that can help inform a broader treatment plan.

A clinical evaluation considers the larger picture before any treatment decision is made. Meet Blue Sky's psychiatric care team.

Practical questions

Spravato Insurance Coverage in Maryland & Washington, DC

Coverage for Spravato varies by insurance plan and may involve prior authorization or other plan-specific requirements. Blue Sky Mental Health Clinic accepts Medicaid and Medicare, but coverage can vary by service and individual benefits. Contact Blue Sky to discuss benefit verification and the next steps before treatment. Coverage and treatment eligibility are not guaranteed.

Does insurance cover Spravato?

Spravato may be covered by some insurance plans, but benefits and authorization requirements vary. Blue Sky can discuss the information needed to review your individual coverage.

Does Spravato require prior authorization?

Some insurance plans may require prior authorization before Spravato treatment. Requirements vary by plan, so benefits should be verified before treatment begins.

Does Blue Sky accept Medicaid and Medicare?

Blue Sky Mental Health Clinic accepts Medicaid and Medicare. Coverage can vary by service and individual benefits, so Spravato-specific coverage should be verified before treatment.

Review Blue Sky's insurance information
Request a Spravato Evaluation

Good questions to ask

Frequently asked questions about Spravato

For more background, read our patient guide to Spravato and esketamine.

Is Spravato approved for treatment-resistant depression?

Yes. Spravato is FDA-approved for treatment-resistant depression in adults. Current labeling permits its use alone or with an oral antidepressant. A separate indication involving acute suicidal ideation or behavior specifies use with an oral antidepressant.

Is Spravato the same as ketamine?

No. Spravato contains esketamine, which is related to ketamine, but it is a distinct FDA-approved nasal spray with specific administration and safety requirements.

Can I take Spravato at home?

No. Spravato must be administered under supervision in a certified healthcare setting through the SPRAVATO REMS program.

How long will I need to stay after treatment?

Patients are monitored for at least two hours following administration. Your care team will explain the monitoring requirements if treatment is appropriate for you.

Is Blue Sky a certified SPRAVATO REMS treatment location?

Yes. Blue Sky Mental Health Clinic provides SPRAVATO treatment in healthcare settings certified in the SPRAVATO REMS. SPRAVATO is administered under the direct observation of a healthcare provider, and patients are monitored for at least two hours after treatment.

Does Blue Sky provide Spravato treatment in Silver Spring, MD?

Yes. Blue Sky provides Spravato treatment at its Silver Spring location. A psychiatric evaluation is required to determine whether it may be appropriate for you.

Does Blue Sky provide Spravato treatment in Laurel, MD?

Yes. Blue Sky provides Spravato treatment at its Laurel location. A psychiatric evaluation is required to determine whether it may be appropriate for you.

Does Blue Sky provide Spravato treatment in Washington, DC?

Yes. Blue Sky provides Spravato treatment at its Washington, DC location. A psychiatric evaluation is required to determine whether it may be appropriate for you.

Will my insurance cover Spravato?

Coverage depends on your individual plan and any authorization requirements. Contact Blue Sky to discuss what information may be needed to review your benefits.

How do I know whether I qualify?

Start with a psychiatric evaluation. A provider reviews your symptoms, previous treatment, medications, medical history, and other factors before discussing whether Spravato may be appropriate.

Request a Spravato Evaluation

The next conversation

You’ve tried treatment. What comes next?

If depression has not improved enough with previous treatment, Blue Sky Mental Health Clinic can evaluate whether Spravato may be one appropriate next step.

Request a Spravato EvaluationCall Blue Sky

A considered next step

Request a Spravato Evaluation

Tell us how to reach you. Our team can follow up about an evaluation and discuss practical next steps. Submitting this form does not establish eligibility or guarantee treatment.

Please do not include diagnoses, medication lists, medical records, or other sensitive health information in this form. This form is not for emergencies. If you need immediate help, call 911 or visit the nearest emergency department.
Your contact details

Spravato is offered at all three offices; an evaluation determines eligibility and next steps.

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